He said consumers could eventually rely on dozens, or even hundreds, of AI agents to coordinate their digital activities, with blockchain networks serving as the financial and identity infrastructure connecting those systems.

“I think the point is that it’s going to be more agents than humans,” Siu said, predicting there could eventually be “50 to 100 billion agents roaming essentially on the internet.”

That shift, he argued, could also solve one of crypto’s longest-running problems: onboarding ordinary users.

While an estimated 700 million to 800 million people globally now own some form of cryptocurrency, Siu noted that fewer than 70 million actively use blockchain applications because crypto remains technically intimidating for mainstream consumers.

“My mom’s not going to be using MetaMask,” he said. “It’s hard for her.”

AI agents, however, may interact naturally with wallets, smart contracts, and decentralized finance systems because they operate directly through code, he argued.

Unlike humans, agents would not need traditional banking infrastructure and could transact autonomously on-chain.

“Blockchain technology is the ideal financial system for machines,” Siu said. “We, the humans, were basically the guinea pigs.”

The broader argument reflected a growing narrative within parts of the crypto industry that blockchain’s most scalable users may ultimately be autonomous software agents rather than humans.

In that framework, wallets, tokens, decentralized identity systems, and on-chain payments become machine infrastructure powering an emerging “agent economy.”

As part of that push, Animoca announced a $10 million investment initiative for developers building AI agent applications through its Animoca Minds platform.

If Siu’s vision materializes, the next major wave of blockchain adoption may not come from millions of new human users learning to navigate crypto wallets, but from billions of AI agents transacting autonomously with one another behind the scenes.

More For You

Alexander Blume, founder and CEO of Two Prime, speaks at Consensus 2026 in Miami (CoinDesk)

At Consensus 2026 in Miami, executives from Two Prime, Ledn and Lygos Finance said institutional borrowers increasingly prioritize custody, transparency and standardized lending structures over complex DeFi products after the crypto credit collapses of 2022.

What to know:

  • Institutional bitcoin lenders are shifting away from complex DeFi structures toward more traditional finance-style practices emphasizing transparency, standardized contracts and clear risk controls.
  • Panelists at Consensus 2026 said institutional borrowers increasingly scrutinize where bitcoin collateral is stored and whether lenders rehypothecate assets, reflecting lessons from the 2022 crypto lending collapses.

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